2012

Eke I, Storch K, Kästner I, Vehlow A, Faethe C, Mueller-Klieser W, Taucher-Scholz G, Temme A, Schackert G, Cordes N. Three-dimensional invasion of human glioblastoma cells remains unchanged by X-ray and carbon ion irradiation in vitro.Int J Radiat Oncol Biol Phys, 2012, 84(4): e515-23

Cordes N, Rödel F, Rodemann HP. Molecular signaling pathways. Mechanisms and clinical use.Strahlenther Onkol, 2012, 188(3): 308-11

Ingargiola M, Dittfeld C, Runge R, Zenker M, Heldt JM, Steinbach J, Cordes N, Baumann M, Kotzerke J, Kunz-Schughart LA. Flow cytometric cell-based assay to preselect antibody constructs for radionuclide conjugation.Cytometry A, 2012, 81(10): 865-73

Mazzeo E, Hehlgans S, Valentini V, Baumann M, Cordes N. The impact of cell-cell contact, E-cadherin and EGF receptor on the cellular radiosensitivity of A431 cancer cells.Radiat Res, 2012, 178(3): 224-33

Hehlgans S, Eke I, Cordes N. Targeting FAK radiosensitizes 3-dimensional grown human HNSCC cells through reduced Akt1 and MEK1/2 signaling.Int J Radiat Oncol Biol Phys, 2012, 83(5): e669-76

Albert M, Schmidt M, Cordes N, Dörr W. Modulation of radiation-induced oral mucositis (mouse) by selective inhibition of β1 integrin.Radiother Oncol, 2012, 104(2): 230-4

Eke I, Dickreuter E, Cordes N. Enhanced radiosensitivity of head and neck squamous cell carcinoma cells by β1 integrin inhibition.Radiother Oncol, 2012, 104(2): 235-42

Eke I, Deuse Y, Hehlgans S, Gurtner K, Krause M, Baumann M, Shevchenko A, Sandfort V, Cordes N. β1Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy.J Clin Invest, 2012, 122(4): 1529-40

Storch K, Cordes N. Focal adhesion-chromatin linkage controls tumor cell resistance to radio- and chemotherapy.Chemother Res Pract, 2012, 2012:319287

Zschenker O, Streichert T, Hehlgans S, Cordes N. Genome-wide gene expression analysis in cancer cells reveals 3D growth to affect ECM and processes associated with cell adhesion but not DNA repair.PLoS One, 2012, 7(4): e34279

2011

Eke I, Deuse Y, Hehlgans S, Gurtner K, Krause M, Baumann M, Shevchenko A, Sandfort V, Cordes N. β1 integrin/FAK/Cortactin signaling is essential for human head and neck cancer resistance to radiotherapy. J Clin Invest, 2012, 122(4):1529-40

Hehlgans S, Eke I, Cordes N. Targeting FAK radiosensitizes 3D grown human HNSCC cells through reduced Akt1 and MEK1/2 signaling. Int J Radiat Oncol Biol Phys, 2012, Apr 6. [Epub ahead of print]

Zschenker O, Streichert T, Hehlgans S, Cordes N. Genome-wide gene expression analysis in cancer cells reveals 3D growth to affect ECM and processes associated with cell adhesion but not DNA repair. PLoS ONE, 7(4):e34279. Epub 2012 Apr 11

Hehlgans S, Lange I, Eke I, Kammerer B, Cordes N. Human head and neck squamous cell carcinoma cell lines are differentially radiosensitized by the honeybee product Propolis. Int J Radiat Biol, 2011, 87(3):243-53

Hehlgans S, Cordes N. Caveolin-1: an essential modulator of cancer cell radio- and chemoresistance. Am J Cancer Res, 2011, 1(4):521-530 

Eke I, Cordes N. Radiobiology goes 3D: How ECM and cell morphology impact on cell survival after irradiation review. Radiother Oncol, 2011, 99(3):271-8 

Eke I, Cordes N. Dual targeting of EGFR and Focal Adhesion Kinase in 3D grown HNSCC cell cultures EGFR. Radiother Oncol, 2011, 99(3):279-86

2010
Sandfort V, Eke I, Cordes N. The role of the focal adhesion protein PINCH1 for the radiosensitivity of adhesion and suspension cell cultures. PLoS ONE, 2010, 5(9): e13056. doi:10.1371/journal.pone.0013056

Eke I, Koch U, Hehlgans S, Sandfort V, Stanchi F, Zips D, Baumann M, Shevchenko A, Pilarsky C, Haase M, Baretton GB, Calleja V, Larijani B, Fässler R, Cordes N (2010) PINCH1 controls Akt for regulating radiation sensitivity by inhibiting PP1alpha. J Clin Invest, Epub 2010 June 1

Storch K, Eke I, Borgmann K, Krause M, Richter C, Becker K, Schröck E, Cordes N (2010) Three-dimensional cell growth confers radioresistance by chromatin density modification. Cancer Res, 70(10):3925-34