Projects (Excerpt, February 2018)

Funding Federal Ministries

SONO RAY
Project Manager: Prof. Dr. M. Krause, Dr. A. Hoffmann
Funding period: 2016-2019
Funding agency: Federal Ministry of Education and Research

Collaborative project: DNA repair foci as markers of individual radiosensitivity. AP 5 Repair foci as potential markers of tumor radiation sensitivity. (KVSF successor)
Project Manager: Prof. Michael Baumann, Dr. Cläre v. Neubeck
Funding period: 2014-2018
Funding agency: Federal Ministry of Education and Research, 02NUK035C


Funding from the German Research Foundation (DFG)

Investigation of the role of a neuropilin-2/CXCR4 signal axis in bone metastasis of prostate cancer
Project Manager: Prof. Dr. Anna Dubrovska
Funding period: 2016-2018
Funding agency: German Research Foundation, DU 1477/2-1

Cellular Radiosensitivity and Endocytosis: The Role of PINCH1 and Caveolin-1
Project Manager: Prof. Nils Cordes
Funding period: 2017-2019
Funding agency: German Research Foundation FKZ: CO 668/8-1

µBONE SPP Pca CSC, Functional Characterization of Bone Metastasis Initiating and Radiation Resistant Cells in Prostate Cancer
Project Manager: Prof. Mechthild Krause, Prof. Dr. Anna Dubrovska
Funding period: 2018-2021
Funding agency: German Research Foundation, FKZ: 401326337


Funding from the German Cancer Aid

Cell adhesion-related radiation resistance of tumor cells: Significance of b1 integrins for DNA repair
Project Manager: Prof. Nils Cordes
Funding period: 2016-2019
Funding agency: German Cancer Aid e.V. FKZ: 112152

Clarification of the adaptation mechanisms induced by inhibition of the discoidin domain receptor 1 (DDR1) to optimize radiochemosensitization of glioblastoma cells
Project Manager: Prof. Nils Cordes
Funding period: 2018-2021
Funding agency: German Cancer Aid e.V. FKZ: 70112889

 

Funding from the European Union

IMMUNOSABR, Phase II study by using stereotactic ablative radiotherapy and immunotherapy with L19-IL2 as a curative Treatment Option for patients with limited metastatic lung cancer
Project Manager: Prof. Esther Troost
Funding period: 2017-2022
Funding agency: European Union, FKZ: 733008

INSPIRE, INfraStructure in Proton International Research
Project Manager: Prof. Esther Troost
Funding period: 2018-2021
Funding agency: European Union, FKZ: 730983

RADIATE-Marie Curie ITN, WP1 Focal Adhesion and Radiosensitivity
Project Manager: Prof. Nils Cordes
Funding period: 2014-2017
Funding agency: European Union, H2020, 642623

 

Other

Characterization and validation of the stem cell transcription factor Oct4 and Oct4-dependent gene signatures as potential radiation resistance biomarkers in head and neck tumors
Project Manager: Prof. Anna Dubrovska
Funding period: 2018-2020
Funding agency: Wilhelm Sander Foundation

Proteins of focal adhesions for therapy resistance and invasion of glioblastoma stem cells: Identification, molecular mechanisms of action and specific inhibition
Project Manager: Prof. Nils Cordes
Funding period: 2017-2019
Funding agency: Wilhelm Sander Foundation

SAKK 09/10 - Can intensified salvage radiotherapy in biochemically relapsed prostate cancer without macroscopic disease
Project Manager: Dr. T. Hölscher
Funding period: 2011-2024
Funding agency: Swiss Group for Clinical Cancer Research (SAKK)