Molecular and Cellular Radiobiology

Publications

2010
Eke I, Koch U, Hehlgans S, Sandfort V, Stanchi F, Zips D, Baumann M, Shevchenko A, Pilarsky C, Haase M, Baretton GB, Calleja V, Larijani B, Fässler R, Cordes N (2010) PINCH1 controls Akt for regulating radiation sensitivity by inhibiting PP1alpha. J Clin Invest, Epub 2010 June 1

Storch K, Eke I, Borgmann K, Krause M, Richter C, Becker K, Schröck E, Cordes N (2010) Three-dimensional cell growth confers radioresistance by chromatin density modification. Cancer Res, 70(10):3925-34

2009

Eke I, Leonhardt F, Storch K, Hehlgans S, Cordes N (2009) The small molecule
inhibitor QLT0267 Radiosensitizes squamous cell carcinoma cells of the head and neck.
PLoS One, 4(7): e6434.

Barcellos-Hoff MH, Cordes N (2009) Resistance to radio- and
chemotherapy and the tumour microenvironment.
Int J Radiat Biol, 85(11): 920-922

Eke I, Hehlgans S, Cordes N (2009) There’s something about ILK.
Int J Radiat Biol, 85(11): 929-936

Hehlgans S, Lange I, Eke I, Cordes N (2009) 3D cell cultures of human head
and neck squamous cell carcinoma cells are radiosensitized by the focal
adhesion kinase inhibitor TAE226.
Radiother Oncol, 92: 371-378

Hehlgans S, Eke I, Storch K, Haase M, Baretton GB, Cordes N (2009)
Caveolin-1 mediated radioresistance of 3D grown pancreatic cancer cells.
Radiother Oncol 92: 362-370

2008

Haase M, Gmach CG, Eke I, Hehlgans S, Baretton GB, Cordes N (2008) Expression of Integrin-linked Kinase Is Increased in Differentiated Cells.
J Histochem Cytochem 56: 819-829.

Hehlgans S, Eke I, Deuse Y, Cordes N (2008) Integrin-linked kinase: Dispensable for radiation survival of three-dimensionally cultured fibroblasts.
Radiother Oncol 86: 329-335.

2007

Barcellos-Hoff MH, Cordes N. Radiation therapy and the microenvironment. Int J Radiat Biol, 2007, 83:723-725

Sandfort V, Koch U, Cordes N. Cell adhesion-mediated radioresistance revisited. Int J Radiat Biol, 2007, 83: 727-732

Eke I, Sandfort V, Storch K, Baumann M, Röper B, Cordes N. Pharmacological inhibition of EGFR tyrosine kinase affects ILK-mediated cellular radiosensitization in vitro. Int J Radiat Biol, 2007, 83: 793-802

Hehlgans S, Eke I, Cordes N. An essential role of integrin-linked kinase in the cellular radiosensitivity of normal fibroblasts during the process of cell adhesion and spreading. Int J Radiat Biol, 2007, 83: 769-779

Cordes N, Park CC. ß1 integrin as a molecular therapeutic target. Int J Radiat Biol, 2007, 83: 753-760

Hehlgans S, Eke I, Deuse Y, Cordes N. Integrin-linked kinase: Dispensable for radiation survival of three-dimensionally cultured fibroblasts. Radiother Oncol, 2007, doi:10.1016/j.radonc.2007.09.007

Cordes N, Frick S, Brunner TB, Pilarsky C, Grutzmann R, Sipos B, Kloppel G, McKenna WG, Bernhard EJ. Human pancreatic tumor cells are sensitized to ionizing radiation by knockdown of caveolin-1. Oncogene, 2007, 26: 6851-6862 >>