2020

Cubillos-Mesías M, Troost EGC, Lohaus F, Agolli L, Rehm M, Richter C, Stützer K.
Quantification of plan robustness against different uncertainty sources for classical and anatomical robust optimized treatment plans in head and neck cancer proton therapy.
Br J Radiol. 2020;93(1107):20190573.

Bütof R, Löck S, Soliman M, Haase R, Perrin R, Richter C, Appold S, Krause M, Baumann M.
Dose-volume predictors of early esophageal toxicity in non-small cell lung cancer patients treated with accelerated-hyperfractionated radiotherapy.
Radiother Oncol. 2020;143:44-50.

Wohlfahrt P, Richter C.
Status and innovations in pre-treatment CT imaging for proton therapy.
Br J Radiol. 2020;93(1107):20190590.

2019

Richter C, Andronesi OC, Borra RJH, Voigt F, Löck S, Duda DG, Guimaraes AR, Hong TS, Bortfeld TR, Seco J.
Inter-patient variations of radiation-induced normal-tissue changes in Gd-EOB-DTPA-enhanced hepatic MRI scans during fractionated proton therapy.
Clin Transl Radiat Oncol. 2019;18:113-119.

Wohlfahrt P, Möhler C, Troost EGC, Greilich S, Richter C.
Dual-Energy Computed Tomography to Assess Intra- and Inter-Patient Tissue Variability for Proton Treatment Planning of Patients With Brain Tumor.
Int J Radiat Oncol Biol Phys. 2019;105(3):504-513.

Werner T, Berthold J, Hueso-González F, Koegler T, Petzoldt J, Roemer K, Richter C, Rinscheid A, Straessner A, Enghardt W, Pausch G.
Processing of prompt gamma-ray timing data for proton range measurements at a clinical beam delivery.
Phys Med Biol. 2019;64(10):105023.

van der Heyden B, Wohlfahrt P, Eekers DBP, Richter C, Terhaag K, Troost EGC, Verhaegen F.
Dual-energy CT for automatic organs-at-risk segmentation in brain- tumor patients using a multi-atlas and deep-learning approach.
Sci Rep. 2019;9(1):4126.

Bandurska-Luque A, Löck S, Haase R, Richter C, Zöphel K, Perrin R, Appold S, Krause M, Steinbach J, Kotzerke J, Hofheinz F, Zips D, Baumann M, Troost EGC.
Correlation between FMISO-PET based hypoxia in the primary tumour and in lymph node metastases in locally advanced HNSCC patients.
Clin Transl Radiat Oncol. 2019;15:108-112.

Cubillos-Mesías M, Troost EGC, Lohaus F, Agolli L, Rehm M, Richter C, Stützer K.
Including anatomical variations in robust optimization for head and neck proton therapy can reduce the need of adaptation.
Radiother Oncol. 2019;131:127-134.

Zwanenburg A, Leger S, Agolli L, Pilz K, Troost EGC, Richter C, Löck S.
Assessing robustness of radiomic features by image perturbation.
Sci Rep. 2019;9(1):614.

Meijers A, Jakobi A, Stützer K, Guterres Marmitt G, Both S, Langendijk JA, Richter C, Knopf A.
Log file-based dose reconstruction and accumulation for 4D adaptive pencil beam scanned proton therapy in a clinical treatment planning system: Implementation and proof-of-concept.
Med Phys. 2019;46(3):1140-1149.

Kurz C, Süss P, Arnsmeyer C, Haehnle J, Teichert K, Landry G, Hofmaier J, Exner F, Hille L, Kamp F, Thieke C, Ganswindt U, Valentini C, Hölscher T, Troost E, Krause M, Belka C, Küfer KH, Parodi K, Richter C.
Dose-guided patient positioning in proton radiotherapy using multicriteria-optimization.
Z Med Phys. 2019;29(3):216-228.

Bandurska-Luque A, Löck S, Haase R, Richter C, Zöphel K, Abolmaali N, Seidlitz A, Appold S, Krause M, Steinbach J, Kotzerke J, Zips D, Baumann M, Troost EGC.
FMISO-PET-based lymph node hypoxia adds to the prognostic value of tumor only hypoxia in HNSCC patients.
Radiother Oncol. 2019;130:97-103.

Leger S, Zwanenburg A, Pilz K, Zschaeck S, Zöphel K, Kotzerke J, Schreiber A, Zips D, Krause M, Baumann M, Troost EGC, Richter C, Löck S.
CT imaging during treatment improves radiomic models for patients with locally advanced head and neck cancer.
Radiother Oncol. 2019;130:10-17.

2018

Annika Jakobi, Rosalind Perrin, Antje Knopf, und Christian Richter. „Feasibility of Proton Pencil Beam Scanning Treatment of Free-Breathing Lung Cancer Patients“. Acta Oncologica 57, 2 (2018): 203–10


Christian Möhler, Tom Russ, Patrick Wohlfahrt, Alina Elter, Armin Runz, Christian Richter, und Steffen Greilich. „Experimental Verification of Stopping-Power Prediction from Single- and Dual-Energy Computed Tomography in Biological Tissues“. Physics in Medicine and Biology 63, 2 (2018): 025001.

Christian Möhler, Patrick Wohlfahrt, Christian Richter, und Steffen Greilich. „Reply to ‚Comment on Methodological Accuracy of Image-Based Electron Density Assessment Using Dual-Energy Computed Tomography‘ Med. Phys. 44, 2429-2437 (2017). Medical Physics 45, 5 (2018): 2349–50.

Patrick Wohlfahrt, Christian Möhler, Christian Richter, und Steffen Greilich. "Evaluation of Stopping-Power Prediction by Dual- and Single-Energy Computed Tomography in an Anthropomorphic Ground-Truth Phantom". International Journal of Radiation Oncology, Biology, Physics 100, 1 (2018): 244-53.

 

2017

Cubillos-Mesías M, Baumann M, Troost ECG, Lohaus F, Löck S, Richter C, Stützer K. Impact of robust treatment planning on single-and multi-field optimized plans for proton beam therapy of unilateral head and neck target volumes. Radiat Oncol 12:190, 2017.

Nenoff L, Priegnitz M, Janssens G, Petzoldt J, Wohlfahrt P, Trezza A, Smeets J, Pausch G, Richter C. Sensitivity of a prompt-gamma slit-camera to detect range shifts for proton treatment verification. Radiother Oncol, 125:534-540, 2017. 

Leger S, Zwanenburg A, Pilz K, Lohaus F, Linge A, Zöphel K, Kotzerke J, Schreiber A, Tinhofer I, Budach V, Sak A, Stuschke M, Balermpas P, Rödel C, Ganswindt U, Belka C, Pigorsch S, Combs SE, Mönnich D, Zips D, Krause M, Baumann M, Troost ECG, Löck S, Richter C. A comparative study of machine learning methods for time-to-event survival data for radiomics risk modelling. Nature Scientific Reports 7:13206, 2017.

Wohlfahrt P, Möhler C, Stützer K, Greilich S, Richter C. Dual-energy CT based proton range prediction in head and pelvic tumor patients. Radiother Oncol 125:526-533, 2017.

Wohlfahrt P, Möhler C, Richter C, Greilich S. Evaluation of stopping-power prediction by dual- and single-energy computed tomography in an anthropomorphic ground-truth phantom. IJROBP 100:244-253, 2018.

Stützer K, Jakobi A, Bandurska-Luque A, Barczyk S, Arnsmeyer C, Löck S, Richter C. Potential proton and photon dose degradation in advanced head and neck cancer patients by intra-therapy changes. JACMP 18:104-113, 2017.

Jakobi A, Perrin R, Knopf A, Richter C. Feasibility of proton pencil beam scanning treatment of free-breathing lung cancer patients. Acta Oncol 56, 2017. 

Lühr A, Löck S, Jakobi A, Stützer K, Bandurska-Luque A, Vogelius IR, Enghardt W, Baumann M, Krause M. Modeling tumor control probability for spatially inhomogeneous risk of failure based on clinical outcome data. Z Med Phys, in press, 2017.

Wohlfahrt P, Möhler C, Greilich S, Richter C. Comment on "Dosimetric comparison of stopping power calibration with dual-energy CT and single-energy CT in proton therapy treatment planning". Medical Physics 44:5533-5536, 2017.

Stützer K, Lin A, Kirk M,  Lin L. Superiority in robustness of multi-field optimization over single-field optimization for pencil-beam proton therapy for oropharynx carcinoma: an enhanced robustness analysis. IJROBP 99:738-749, 2017.

Möhler C, Wohlfahrt P, Richter C, Greilich S. Methodological accuracy of image-based electron-density assessment using dual-energy computed tomography. Medical Physics 44:2429-2437, 2017.

Zschaeck S, Löck S, Leger S, Haase R, Bandurska-Luque A, Appold S, Kotzerke J, Zips D, Richter C, Gudziol V, Schreiber A, Zöphel K, Baumann M, Krause M. FDG uptake in normal tissues assessed by PET during treatment has prognostic value for treatment results in head and neck squamous cell carcinomas undergoing radiochemotherapy. Radiother Oncol 122:437-444, 2017.

Brion E, Richter C, Macq B, Stützer K, Exner F, Troost E, Hölscher T, Bondar L. Modeling patterns of anatomical deformations in prostate patients undergoing radiation therapy with an endorectal ballon. Proc. SPIE 10135, Medical Imaging 2017: Image-Guided Procedures, Robotic Interventions, and Modeling, 1013506, 2017.

Wohlfahrt P, Möhler C, Hietschold V, Menkel S, Greilich S, Krause M, Baumann M, Enghardt W, Richter C. Clinical implementation of dual-energy CT for proton treatment planning on pseudo-monoenergetic CT scans. IJROBP 97:427-434, 2017.

 

2016

Priegnitz M, Barczyk S, Nenoff L, Golnik C, Keitz I, Werner T, Mein S, Smeets J, Vander Stappen F, Janssens G, Hotoiu L, Fiedler F, Prieels D, Enghardt W, Pausch G, Richter C. Towards clinical application: prompt gamma imaging of passively scattered proton fields with a knife-edge slit camera. Phys Med Biol 61:7881-7905, 2016.

Stützer K, Haase R, Lohaus F, Barczyk S, Exner F, Löck S, Rühaak J, Lassen-Schmidt B, Cörr D, Richter C. Evaluation of a deformable registration algorithm for subsequent lung computed tomography imaging during radiochemotherapy. Medical Physics 53:5028-5039, 2016.

Zschaeck S, Simon M, Löck S, Troost ECG, Stützer K, Wohlfahrt P, Appold S, Makocki S, Bütof R, Richter C, Baumann M, Krause M. PRONTOX – proton therapy to reduce acute normal tissue toxicity in locally advanced non-small-cell lung carcinomas (NSCLC): study protocol for a randomised controlled trial. Trials 17:543, 2016.

Knopf AC, Stützer K, Richter C, Rucinski A, da Silva J, Phillips J, Engelsman M, Shimizu S, Werner R, Jakobi A, Göksel O, Zhang Y, Oshea T, Fast M, Perrin R, Bert C, Rinaldi I, Korevaar E, McClelland J. Required transition from research to clinical application: Report on the 4D treatment planning workshops 2014 and 2015. Physica Medica 32:874-882, 2016.

Möhler C, Wohlfahrt P, Richter C, Greilich S. Range prediction for tissue mixtures based on dual-energy CT. Phys Med Biol 61:N268-N275, 2016.

Baumann M, Krause M, Overgaard J, Debus J, Bentzen SM, Daartz J, Richter C, Zips D, Bortfeld T. Radiation oncology in the era of precision medicine. Nature Review Cancer 16:234–249, 2016.

Richter C, Pausch G, Barczyk S, Priegnitz M, Keitz I, Thiele J, Smeets J, Vander Stappen F, Bombelli L, Fiorini C, Hotoiu L, Perali I, Prieels D, Enghardt W, Baumann M. First clinical application of a prompt gamma based in vivo proton range verification system. Radiother Oncol 118:232-237, 2016.

 

2015

Jakobi A, Bandurska-Luque A, Stützer K, Haase R, Löck S, Wack LJ, Mönnich D, Thorwarth D, Perez D, Lühr A, Zips D, Krause M, Baumann M, Perrin R, Richter C. Identification of patient benefit from proton therapy for advanced head and neck cancer patients based on individual and subgroup NTCP analysis. IJROBP 92:1165-1174, 2015.

Jakobi A, Stützer K, Bandurska-Luque A,  Löck S, Haase R, Wack LJ, Mönnich D, Thorwarth D, Perez D, Lühr A, Zips D, Krause M, Baumann M, Perrin R, Richter C. NTCP reduction for advanced head and neck cancer patients using proton therapy for complete or sequential boost treatment versus photon therapy. Acta Oncol 54:1658-64, 2015.

Zschaeck S, Haase R, Abolmaali N, Perrin R, Stützer S, Appold S, Steinbach J, Kotzerke J, Zips D, Richter C,
Gudziol V, Krause M, Zöphel K, Baumann M. Spatial distribution of FMISO in head and neck squamous cell carcinomas during radio-chemotherapy and its correlation to pattern of failure. Acta Oncol 54:1355-63, 2015.

Jakobi A, Lühr A,  Stützer K, Bandurska-Luque A, Löck S, Krause M, Baumann M, Perrin R, Richter C. Increase in Tumor Control and Normal Tissue Complication Probabilities in Advanced Head-and-Neck Cancer for Dose-Escalated Intensity-Modulated Photon and Proton Therapy. Front Oncol 5:256, 2015.

 

2014

Richter C, Seco J, Hong TS, Duda DG, Bortfeld T. Radiation-induced changes in hepatocyte-specific Gd-EOB-DTPA enhanced MRI: potential mechanism. Med Hypotheses. 83(4):477-481, 2014. 

Knopf A, Nill S, Yohannes I, Graeff C, Dowdell S, Kurz C, Sonke JJ, Biegun AK, Lang S, McClelland J, Champion B, Fast M, Wölfelschneider J, Gianoli C, Rucinski A, Baroni G, Richter C, van de Water S, Grassberger C, Weber D, Poulsen P, Shimizu S, Bert C. Challenges of radiotherapy: Report on the 4D treatment planning workshop 2013. Phys Medica 30:809-815, 2014. 

Wink KC, Roelofs E, Solberg T, Lin L, Simone CB 2nd, Jakobi A, Richter C, Lambin P, Troost EG. Particle therapy for non-small cell lung tumors: where do we stand? A systematic review of the literature. Front Oncol 4:292, 2014.   

Lühr A, Löck S, Roth K, Helmbrecht S, Jakobi A, Petersen JB, Just U, Krause M, Enghardt W, Baumann M. Concept for individualized patient allocation: ReCompare—remote comparison of particle and photon treatment plans. Radiat Oncol 9:59, 2014.