2015

Erven AJG, van der Stoep J, Zegers K, Reymen B, Lambin P, Troost EGC, van Elmpt W. PET-based dose painting in non-small cell lung cancer: comparing uniform dose escalation with boosting hypoxic and metabolically active sub-volumes. Accepted for publication in Radiother Oncol.

Hendriks LE, Derks J, Postmus PE, Damhuis RA, Houben RM, Troost EGC, Hochstenbag MM, Smit EF, Dingemans AM. Single organ metastatic disease, a new prognostic factors in stage IV Non-Small Cell Lung Cancer. Accepted for publication in Eur J Cancer.

Hermans BCM, Persoon LC, Hoebers FJP, Verhaegen F, Troost EGC. Weekly cone beam computed tomography for detection of discrepancies between planned and delivered dose in head and neck cancer patients treated with radical (chemo)radiotherapy. E-pub ahead of print in Acta Oncol.

Jentsch C, Beuthien-Baumann B, Troost EGC, Shakirin G (2015) Validation of functional imaging results as a biomarker for radiation treatment response. Br J Radiol 88: 20150014

Leijenaar RTH, Nalbantov G, Carvalho S, van Elmpt WJC, Troost EGC, Boellaard R, Aerts HJWL, Lambin P. The effect of SUV discretization in quantitative FDG-PET Radiomics: the need for standardized methodology in tumor texture analysis. Accepted for publication in Nature Scientific Reports.

Persoon LCGG, Podesta M, Hoffmann L, Sanizadeh A, Schyns LEJR, de Ruiter B, Nijsten SMJJG, Muren LP, Troost EGC, Verhaegen F. Is integrated transit planar portal dosimetry able to detect geometric changes in lung cancer patients treated with volumetric modulated arc therapy? E-pub ahead of print in Acta Oncol.

Schimek-Jasch T, Troost EGC, Rücker G, Prokic V, Avlar M, Duncker-Rohr V, Mix M, Doll C, Gorsu AL, Nestle U (2015) A teaching intervention in a contouring dummy run for a multicentre clinical study improved target volume delineation in locally advanced non-small cell lung cancer. Strahlenth Onkol: 525-533

Troost EGC, Hoeben BAW, Laverman P, Bussink J, Oyen WJG (2015) In response to “Histopathologic validation of 3’-deoxy-3’-18F-fluorothymidine PET for detecting tumour repopulation during fractionated radiotherapy in human FaDu squamous cell carcinoma in nude mice”. Radiother Oncol 114: 417-418

van Elmpt W, Zegers CML, Reymen B, Even A, Dingemans AMC, Oellers M, Wildberger J, Mottaghy F, Das M, Troost EGC, Lambin P. Multi-parametric imaging of hypoxic, metabolic and perfusion tumour characteristics of non-small cell lung cancer patients for tumour heterogeneity quantification. Accepted for publication in Eur J Nucl Med Molec Imaging.

Wijsman R, Dankers F, Troost EGC, Hoffmann AL, Van der Heijden EHFM, de Geus-Oei LF, Bussink J. Predicting acute esophageal toxicity in advanced stage non-small cell lung cancer patients treated with intensity-modulated (chemo-) radiation. Accepted for publication in Radiother Oncol.

Wink K, Roelofs E, Solberg T, Lin L, Simone CB, Jakobi A, Richter C, Lambin P, Troost EGC (2015) Particle therapy for non-small cell lung tumors: where do we stand? A systematic review of the literature. Radiat Oncol: 292

Zegers CML, Rekers NH, Quaden DHF, Lieuwes NG, Yaromina A, Germeraad WTV, Wieten L, Biessen E, Neri D, Troost EGC, Dubois L, Lambin P (2015) Radiotherapy combined with targeted immunotherapy (L19-IL2) results in long-lasting anti-tumor effects. Clin Cancer Res: 1151-1160

Zegers CML, Van Elmpt, W, Hoebers FJP, Troost EGC, Öllers MC, Mottaghy F, Lambin P. Imaging of tumour hypoxia and metabolism in patients with head and neck squamous cell carcinoma. E-pub ahead of print in Acta Oncol.

 

2014

Arens AIJ*, Troost EGC*, Hoeben BAW, Visvikis D, Bussink J, Oyen WJG, Kaanders JHAM, Visser EP (2014) Comparison of multiple (semi-)automatic segmentation methods for delineation of proliferative head and neck tumor volume in sequential FLT PET/CT imaging. Eur J Nucl Med Mol Imag 41: 915-924, *shared first author

Hendriks LEL, Troost EGC, Steward A, Bootsma G, de Jaeger K, van den Borne B, Dingemans AMC (2014) Impact of new Dutch guideline on brain metastases on patient selection for whole brain radiotherapy in a large lung cancer cohort. Acta OncoI 53: 945-951

Hoeben BAW, Bussink J, Troost EGC, Oyen WJG, Kaanders JHAM (2014) PET voor adaptatie van radiotherapieplanning bij hoofd-hals carcinomen. NederlandsTijdschrift voor Oncologie 11: 261-267 (Dutch)

Hoeben BAW, Troost EGC, Bussink J, van Herpen CM, Oyen WJG, Kaanders JHAM (2014) 18F-FLT PET changes during Radiotherapy combined with Cetuximab in Head and Neck Squamous Cell Carcinoma Patients. Nuklearmedizin 53: 60-66

Rekers NH*, Troost EGC*, Zegers CML, Germeraad WTV, Dubois L, Lambin P (2014) Bi-modal treatment consisting of radiotherapy and immunotherapy; what’s the present status? Cancer Radiotherapie 18: 391-395, *shared first author

Smits KM, Melotte V, Niessen HEC, Dubois L, Oberije C, Troost EGC, Starmans M, Vooijs M, van Engeland M, Lambin P (2014) Epigenetic biomarkers in radiotherapy: the current status. Radiother Oncol 111: 168-177

Troost EGC (2014) Stereotaktische Radiotherapie voor Oligometastasen. Van palliatieve behandeling naar curatieve intentie. Oncology News International

Van De Voorde L, Pijls M, Sosef M, Larue R, Berbée M, Troost EGC, Schraepen MC, Oellers M, Lambin P (2014) A qualitative synthesis of the evidence behind elective lymph node irradiation in oesophageal cancer. Radiother Oncol 113: 166-174

Van De Voorde L, Vanneste B, Borger J, Troost EGC, Werner P (2014) Rapid decline of follicular lymphoma-associated chylothorax after low dose radiotherapy to retroperitoneal lymphoma localization. Case Reports in Hematology: ID 684689

 

 

2013

Carvalho S, Leijenaar R, Rios Velazquez E, Oberije C, Van Elmpt W, Reymen B,  Troost EGC, Aerts HJWL, Lambin P (2013) Prognostic usefulness of metabolic metrics extracted from baseline PET images in NSCLC. Acta Oncol 52: 1398-1404

Hoeben BAW, Bussink J, Troost EGC, Oyen WJG and Kaanders JHAM (2013) Molecular PET Imaging for Biology-Guided Adaptive Radiotherapy of Head and Neck Cancer. Acta Oncol 52: 1257-1271

Hoeben BAW*, Troost EGC*, van Herpen CM, Bussink J, Oyen WJG, Kaanders JHAM (2013) 18FLT-PET is an early predictor of long-term outcome during (chemo)radiotherapy in head and neck cancer patients. J Nucl Med 54: 532-540, *shared first author

Hoebers F, Rios E, Troost EGC, van den Ende P, Kross K, Lacko M, Lalisang R, Kremer B, de Jong J (2013) Definitive radiation therapy for treatment of laryngeal carcinoma: Impact of local relapse on outcome and implications for treatment strategies. Strahlenther Onkol 189: 834-841

Lambin P, Roelofs E, Reymen B, Rios Velazquez E, Buijsen J, Zegers K, Carvalho S, Leijenaar R, Nalbantov G, Oberije C, Marshall S, Hoebers F, Troost EGC, van Stiphout RGPM, van Elmpt W, van der Weijden T, Boersma L, Valentini V, Dekker A (2013) ‘Rapid Learning Health Care in Oncology’ – An approach towards decision support systems allowing customised radiotherapy. Radiother Oncol 109: 159-164

Mönnich D, Troost EGC, Kaanders JHAM, Oyen WJG, Alber M, Zips D, Thorwarth D (2013) Correlation between tumor oxygenation and 18F-Fluoromisonidazole PET data simulated based on microvessel images. Acta Oncol 52: 1308-1313

Nalbantov G, Kietselaer B, Vandecasteele K, Oberije C, Berbee M, Troost EGC, Dingemans AM, van Baardwijk A, Reymen B, Smits KM, Dekker A, Bussink J, Lievens Y, Lambin P (2013) Cardiac comorbidity is an independent risk factor for radiation-induced lung toxicity in lung cancer patients. Radiother Oncol 109: 100-106

Persoon LCGG, Egelmeer AGTM, Öllers MC, Nijsten SMJJG, Troost EGC, Verhaegen F (2013) First clinical results of adaptive radiotherapy based on 3D portal dosimetry for lung cancer patients with atelectasis treated with Volumetric Modulated Arc Therapy (VMAT). Acta Oncol 52: 1484-1489

Troost EGC, Hoeben BAW, Span PN, van Herpen CML, Bussink J, Arens AIJ, Oyen WJG, Kaanders JHAM (2013) FLT-PET gedurende (chemo)radiotherapie als vroegtijdige voorspeller van behandeluitkomst bij hoofd-hals-tumoren. NederlandsTijdschrift voor Oncologie 10: 308-317 (Dutch)

Troost EGC, Hoffmann AL, Bussink J (2013) Balancing radiation pneumonitis versus locoregional tumor control in non-small cell lung cancer. JTO 8: e35-e36

Usmanij EA, de Geus-Oei LF, Troost EGC,  Peters-Bax L, van der Heijden HFM, Kaanders JHAM, Oyen WJG, Schuurbiers OCJ, Bussink J (2013) 18F-FDG-PET Early Response Evaluation of Locally Advanced Non-Small Cell Lung Cancer treated with Concomitant Chemo-Radiotherapy. J Nucl Med 54: 1528-1534

van Elmpt W, Das M, Hüllner M, Sharifi H, Zegers K, Reymen B, Lambin P, Wildberger JE, Troost EGC, Veit-Haibach P, De Ruysscher D. Characterization tumour heterogeneity using dynamic contrast enhanced CT and FDG-PET in non-small cell lung cancer (2013) Radiother Oncol 109: 65-70

Van Gestel K, Buurman DJM, Pijls R, Hoffmann AL, Troost EGC. HDR-brachytherapy instead of hemi-maxillectomy for a patient with locally advanced verrucous carcinoma of the oral cavity (2013) Strahlenther Onkol 189: 894-898

Zegers CML, Van Elmpt W, Wierts R,  Sharifi H, Reymen B, Öllers MC, Hoebers F, Troost EGC, Wanders S, Van Baardwijk A, Eriksson J, Windhorst B , Mottaghy FM, De Ruysscher D, Lambin P (2013) Hypoxia imaging with [18F]HX4 PET in NSCLC patients: defining optimal imaging parameters. Radiother Oncol 109: 58-64

 

 

2012

Govaert SLA, Troost EGC, Schuurbiers OCJ, de Geus-Oei LF, Termeer A, Span PN, Bussink J (2012) Treatment outcome and toxicity of intensity-modulated (chemo)radiotherapy in stage III non-small cell lung cancer patients. Radiat Oncol 7: 150

Hoffmann AL, Troost EGC, Huizenga H, Kaanders JHAM, Bussink J (2012) Individualized dose prescription for hypofrationation in advanced non-small cell lung cancer radiotherapy: an in silico trial. Int J Radiat Oncol Biol Phys 83: 1596-1602

Idema AJ, Hoffmann AL, Troost EGC, Boogaarts HD, Wesseling P, Heerschap A, van der Graaf WTA, Grotenhuis JA, Oyen WJG (2012) 18F-Fluorothymidine (FLT) Positron Emission Tomography-derived proliferative tumor volume predicts survival in high-grade glioma patients. J Nucl Med 53: 1904-1910

Mönnich D, Troost EGC, Kaanders JHAM, Oyen WJG, Alber M, Thorwarth D (2012) Modelling and simulation of the influence of acute and chronic hypoxia on [18F]Fluoromisonidazole PET imaging. Phys Med Biol 57: 1675-1684

Zegers C, Reymen R, Buijsen J, van Stiphout R, Peeters S, Lammering G, Hoebers F, Troost EGC, van Baardijk A, Oellers M, van Elmpt W, Lambin P (2012) De bijdrage van PET-beeldvorming in radiotherapie. Het voorbeeld van long- en rectumkanker. Kanker Breed 4: 18-21 (Dutch)

 

 

2011

Aarntzen EHJG, Srinivas M, Jacobs, HJF, Lesterhuis WJ, Windhorst B, Troost EGC, van Rossum M, Boerman OC, Punt CJA, Figdor CF, Oyen, WJG, de Vries J (2011) [18F]FLT PET for in vivo functional imaging of antigen specific immune responses in humans. Proc Natl Acad Sci 108: 18396-18399

Arens AIJ*, Troost EGC*, Schinagl DAX, Kaanders JHAM, Oyen WJG (2011) FDG-PET/CT in radiation treatment planning of head and neck squamous cell carcinoma. Quart J Nucl Med Mol Imaging 55: 521-528, *shared first author

Mönnich D, Troost EGC, Kaanders JHAM, Oyen WJG, Alber M, Thorwarth D (2011) Modelling and simulation of [18F]fluoromisonidazole dynamics based on histology-derived microvessel maps. Phys Med Biol 56: 2045-2057

Troost EGC (2011) Proefschriftbespreking “Validation of PET imaging for non-invasive characterization of head and neck tumors”. NederlandsTijdschrift voor Oncologie 8: 44-46 (Dutch)

 

 

2010

Hoeben BAW, Kaanders JHAM, Franssen GM, Troost EGC, Rijken PFJW Oosterwijk E, van Dongen GAMS, Oyen WJG, Boerman OC, Bussink J (2010) PET of hypoxia with 89Zr-labeled cG250-F(ab’)2 in head and neck tumors. J Nucl Med 51: 1076-1083

Troost EGC (2010) Proefschriftbespreking “Validation of PET imaging for non-invasive characterization of head and neck tumors”. Hoofd-Hals Journaal 22: 39 (Dutch)

Troost EGC (2010) Validation of PET imaging for non-invasive characterization of head and neck tumors. Proefschriftbespreking. Tijdschr Nucl Geneesk 32: 512-513 (Dutch)

Troost EGC, Bussink J, Hoffmann AL, Boerman OC, Oyen WJG, Kaanders JHAM (2010) 18FLT-PET-CT for early response monitoring and dose escalation in oropharyngeal tumor. J Nucl Med 51: 866-874

Troost EGC, Bussink J, Slootweg PJ, Peeters WJM, Merkx MAW, van der Kogel AJ, Oyen WJG, Kaanders JHAM (2010) Histopathological validation of 18FLT-PET in squamous cell carcinoma of the oral cavity. J Nucl Med 51: 713-719

Troost EGC, Schinagl DAX, Bussink J, Oyen WJG, Boerman OC, Kaanders JHAM (2010) Correlation of segmented metabolic tumor volume with outcome. In response to Chung et al. Clin Cancer Res 16: 1968

Troost EGC, Schinagl DAX, Bussink J, Boerman OC, van der Kogel AJ, Oyen WJG, Kaanders JHAM (2010) Innovations in radiotherapy planning of head and neck cancers: role of PET imaging. J Nucl Med 51: 66-76

Troost EGC, Schinagl DAX, Bussink J, Oyen WJG, Kaanders JHAM (2010) Clinical evidence on PET-CT for radiation therapy planning in head and neck tumours. Radiother Oncol 96: 328-334

 

 

2009

Schinagl DAX, Troost EGC, Kaanders JHAM (2009) Combined 18FDG-PET/CT imaging in radiotherapy target delineation for head and neck cancer. In response to Guido et al. Int J Radiat Oncol Biol Phys 74: 1629

Troost EGC, Bussink J, Oyen WJG, Kaanders JHAM (2009) 18F-FDG and 18F-FLT do not discriminate between reactive and metastatic lymph nodes in oral cancer patients. In response to Nagakawa et al. J Nucl Med 50: 490-491

Troost EGC, Oyen WJG, Kaanders JHAM (2009) The role of PET in radiotherapy of head and neck cancers. Tijdschr Nucl Geneesk 31: 403-410 (Dutch)

 

 

2008

Troost EGC, Laverman P, Kaanders JHAM, Oyen WJG, Boerman OC, Bussink J (2008) Intratumoral spatial distribution of hypoxia and angiogenesis assessed by 18FAZA and 125I-Gluco-RGD autoradiography. In response to Picchio et al. J Nucl Med 49: 1732

Troost EGC, Laverman P, Philippens MEP, Bussink J, van der Kogel AJ, Oyen WJG, Boerman OC, Kaanders JHAM (2008) Correlation of 18FMISO autoradiography and pimonidazole immunohistochemistry in human head and neck carcinoma xenografts. Eur J Nucl Med Mol Imaging 35: 1803-1811

 

 

2007

Troost EGC, Bussink J, Kaanders JHAM (2007) Inhibitie van EGFR bij bestraling van plaveiselcelcarcinomen in het hoofd- halsgebied. Ned Tijdschr Kanker 31: 14-18 (Dutch)

Troost EGC, Vogel WV, Merkx MAW, Slootweg PJ, Marres HAM, Peeters WJM, Bussink J, van der Kogel AJ, Oyen WJG, Kaanders JHAM. 18FLT-PET does not discriminate between reactive and metastatic lymph nodes in primary head and neck cancer patients (2007) J Nucl Med 48: 726-735

 

 

2006

Troost EGC, Laverman P, Kaanders JHAM, Philippens MEP, Lok J, Oyen WJG, van der Kogel AJ, Boerman OC, Bussink J (2006) Imaging hypoxia after oxygenation-modification: comparing 18FMISO autoradiography with pimonidazole immunohistochemistry in human xenograft tumours. Radiother Oncol 80: 157-164

 

 

2005

Troost EGC, Bussink J, Kaanders JHAM, van Eerd JEM, Peters JPW, Rijken PFJW, Boerman OC, van der Kogel AJ (2005) Comparison of different methods of CA-IX quantification in relation to hypoxia in three human head and neck tumour lines. Radiother Oncol 76: 194-199

 

 

2003

Troost EGC, Hold GL, Smith MG, Mowat A, Chow W-H, Rabkin CS, El-Omar EM (2003) The role of interleukin-1beta and other potential genetic markers as indicators of gastric cancer risk. Can J Gastroenterol 17: 8B-12B

Troost EGC, Hold GL, Smith MG, Mowat A, Chow W-H, Rabkin CS, El-Omar EM (2003) The role of interleukin-1beta and other potential genetic markers as indicators of gastric cancer risk. Helicobacter pylori: Basic Mechanisms to Clinical Cure, Editors Hunt RH & Tytgat GNJ, Kluwer Academic Publishers: 215-223